Low Level Laser Irradiation Alters Cardiac Cytokine
Expression Following Acute Myocardial Infarction:
A Potential Mechanism for Laser Therapy
Photomedicine and Laser Surgery
Volume 29, Number 6, 2011
In the present study, the antibody-based protein array
technology was applied for screening the cytokine expression
profile following MI, with or without laser irradiation.
The present study indicates that LLLI has a protective effect
on the injured myocardium by upregulating GM-CSF and
downregulating fractalkine during the acute phase after LLLI.
In a future study, we will apply the whole proteome analysis
to analyze the alteration of more cytokines involved in inflammation
at various points in time after laser irradiation.
The cytokine expression profile after laser irradiation offers a
potential novel mechanism
Zhikai Yang, M.D.,1,2,3,* Yihe Wu, M.D.,1,2,* Hao Zhang, M.D., Ph.D.,1,2 Peifeng Jin, M.D.,2,4
Wei Wang, M.D., Ph.D.,2,5 Jianfeng Hou, M.D., Ph.D.,2 Yingjie Wei, Ph.D.,2 and Shengshou Hu, M.D.1,2
Hao Zhang, M.D., Ph.D.
Department of Cardiac Surgery
Cardiovascular Institute & Fu Wai Hospital
167 Beilishi Road
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